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- SinSR: Diffusion-Based Image Super-Resolution in a Single Step378
This work first derive a deterministic sampling process from the most recent state-of-the-art (SOTA) method for accelerating diffusion-based SR, which can be distilled into a student model that performs SR within only one inference step, resulting in a remarkable up to × 10 speedup for inference.
- LMMs-Eval: Reality Check on the Evaluation of Large Multimodal Models373
This work introduces LMMS-EVAL, a unified and standardized multimodal benchmark framework with over 50 tasks and more than 10 models to promote transparent and reproducible evaluations, and introduces LMMS-EVAL LITE, a pruned evaluation toolkit that emphasizes both coverage and efficiency.
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- EgoLife: Towards Egocentric Life Assistant113
This work introduces EgoLife, a project to develop an egocentric life assistant that accompanies and enhances personal efficiency through AI-powered wearable glasses, and introduces EgoBulter, an integrated system comprising EgoGPT and EgoRAG, an integrated system trained on egocentric datasets.
- Scaling Spatial Intelligence with Multimodal Foundation Models85
This work explores scaling up multimodal foundation models to cultivate spatial intelligence within the SenseNova-SI family, built upon established multimodal foundations including visual understanding models and unified understanding and generation models (i.e., Bagel).
- MVPaint: Synchronized Multi-View Diffusion for Painting Anything 3D41
This work proposes a novel generation-refinement 3D texturing framework called MVPaint, which can generate high-resolution, seamless textures while emphasizing multi-view consistency and surpasses existing state-of-the-art methods in texturing.
- OpenMMReasoner: Pushing the Frontiers for Multimodal Reasoning with an Open and General Recipe41
This work introduces OpenMMReasoner, a fully transparent two-stage recipe for multimodal reasoning spanning supervised fine-tuning (SFT) and reinforcement learning (RL), which achieves a 11.6% improvement over the Qwen2.5-VL-7B-Instruct baseline across nine multimodal reasoning benchmarks.
- Elemene Hydrogel Modulates the Tumor Immune Microenvironment for Enhanced Treatment of Postoperative Cancer Recurrence and Metastases38
An ELE hydrogel with controlled drug release kinetics that can allow ELE to maintain effective concentrations at local lesion sites for extended periods to enhance the bioavailability of ELE is reported.
- Towards Video Thinking Test: A Holistic Benchmark for Advanced Video Reasoning and Understanding31
The Video Thinking Test (Video-TT) is introduced, to assess if video LLMs can interpret real-world videos as effectively as humans and shows a significant gap between video LLMs and human performance.
- Nanobiotechnology boosts ferroptosis: opportunities and challenges30
This review provides an extensive introduction to the background of ferroptosis and discusses the various advantages of combining nanobiotechnology with ferroptosis to enhance therapeutic efficacy and reduce the side effects of ferroptosis-associated diseases.
- WorldLens: Full-Spectrum Evaluations of Driving World Models in Real World29
This work introduces WorldLens, a full-spectrum benchmark evaluating how well a model builds, understands, and behaves within its generated world, and develops WorldLens-Agent, an evaluation model distilled from these annotations to enable scalable, explainable scoring.
- Robust Sequential DeepFake Detection29
The first Seq-DeepFake dataset is constructed, where face images are manipulated sequentially with corresponding annotations of sequential facial manipulation vectors, and a dedicated Seq-DeepFake Transformer with Image-Sequence Reasoning is devised, which builds stronger correspondence between image-sequence pairs for more robust Seq-DeepFake detection.
- lncRNA HEIH accelerates cell proliferation and inhibits cell senescence by targeting miR-3619-5p/CTTNBP2 axis in ovarian cancer25
The research revealed that HEIH accelerated cell proliferation, migration and invasion, whereas inhibited cell senescence in ovarian cancer via targeting the miR-3619-5p/CTTNBP2 axis and may be valuable for finding new therapeutic targets to improve ovarian cancer treatment.
- LongVie: Multimodal-Guided Controllable Ultra-Long Video Generation22
LongVie, an end-to-end autoregressive framework for controllable long video generation, introduces two core designs to ensure temporal consistency: a unified noise initialization strategy that maintains consistent generation across clips, and global control signal normalization that enforces alignment in the control space throughout the entire video.
- Move Anything with Layered Scene Diffusion18
This work proposes SceneDiffusion to optimize a layered scene representation during the diffusion sampling process, and finds that spatial disentanglement can be obtained by jointly denoising scene rende rings at different spatial layouts.
- Chanoclavine synthase operates by an NADPH-independent superoxide mechanism14
The unique structure and mechanism of chanoclavine synthase (EasC), a haem catalase that uses superoxide for substrate transformation in ergot alkaloid biosynthesis, are revealed in this study, challenging established catalase mechanisms.
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- LongVie 2: Multimodal Controllable Ultra-Long Video World Model10
LongVie 2 is presented, an end-to-end autoregressive framework trained in three stages that achieves state-of-the-art performance in long-range controllability, temporal coherence, and visual fidelity, and supports continuous video generation lasting up to five minutes, marking a significant step toward unified video world modeling.
- Effective treatment of refractory aplastic anemia with romiplostim after failure of multiple thrombopoietin receptor agonists: a single-center retrospective study9
High-dose ROM with an initial dosage of 20 μg/kg per week is effective and safe for patients with refractory aplastic anemia who experienced treatment failure with immunosuppressive therapy and multiple oral thrombopoietin receptor agonists.
- RY10-4, a novel anti-tumor compound, exhibited its anti-angiogenesis activity by down-regulation of the HIF-1α and inhibition phosphorylation of AKT and mTOR9
The structure of 4-hydroxy-2,5-cyclohexadien-1-one should be the effective pharmacophore of RY10-4 and will be the new hot-spot for further anti-tumor agency development.
- Graph theory analysis of a human body metabolic network: A systematic and organ‐specific study8
This work proposes a graph‐based analysis method for quantifying the topological properties of the network, both globally and at the nodal level, to detect systemic or single‐organ metabolic abnormalities caused by diseases such as lung cancer.
- Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB28
Mechanically, overexpression of miR-155-3p can reduce the secretion of TNF-α in RAW264.7 cells, revealing a possible mechanism ofMiRNAs regulating RT-induced inflammatory injury and reveals the potential role of miRNAs in innate immune regulation.
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- Targeting multiple genetic defects of mitochondrial diseases with a single bacterial lipoate protein ligase4
Overexpressing LplA through a mating strategy rescued embryonic lethality in Lipt1−/− mutants, yielding viable offspring with normal body weight, energy expenditure, tissue morphology, and biochemical profile, highlighting how evolutionary differences in biosynthetic pathways between humans and bacteria can be leveraged for cross-species therapeutic innovations.
- Long-Term Experience with Luspatercept in Relapsed/Refractory Myelodysplastic Neoplasms: A Chinese Real-World Study4
Luspatercept is proved efficacious and well tolerated in relapsed/refractory LR-MDS and appears to be beneficial in reducing disease progression and prolonging survival.
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- Restoration of A2M reduces drug resistance and malignancy in paclitaxel-resistant lung cancer cells3
A2M deficiency may serve as both a predictor and a therapeutic target for paclitaxel resistance in lung cancer, and restoring A2M may help overcome this resistance.
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- Metabolic network analysis of lung adenocarcinoma and squamous cell carcinoma via static and dynamic total‐body PET/CT imaging2
Allowing for early noninvasive differentiation remains challenging in lung adenocarcinoma and squamous cell carcinoma subtypes, necessitating tailored treatments, remains challenging.
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- Risk Factors, Manifestations, and Implications of Chyle Leak following Pancreatic Surgery2
Post-pancreatectomy patients with large-volume, TG-rich but non-milky drainage should be treated like clinically relevant CL, and minimally invasive approach and daily maximum drainage volume were independent risk factors for CL in this cohort.
- High expression levels of centromere protein O participates in cell proliferation of human ovarian cancer2
This study indicates that CENP-O has the potential to be a molecular therapeutic target, and downregulating the expression of CENP-O gene can break the unlimited proliferation ability of cancer cells and promote their apoptosis, providing a foundation and new ideas for subsequent molecular mechanism research and targeted therapy.
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- Engineering immune-competent niches: strategies, applications, and translational hurdles in ovarian cancer organoid models1
This review discusses the organoid construction methods using adult stem cells, and induced pluripotent stem cells, comparing various culture platforms from air–liquid interface to microfluidic devices, and highlights organoids containing immune components are valuable for assessing T cell exhaustion, NK cell cytotoxicity, and stromal communication.
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- Computational Study on the Reaction Mechanism of 5‐Enolpyruvylshikimate‐3‐phosphate Synthase from Nicotiana Tabacum1
The calculations suggest a step‐wise mechanism for the formation of the tetrahedral intermediate by the proton transfer from the hydroxyl group of S3P to Asp331 and the nucleophilic attack of hydroxyl group on the carbocation, which is consistent with the proposal in literature.
- Adding recombinant human thrombopoietin to cyclosporine A and hetrombopag enhances the early hematologic response in transfusion-dependent non-severe aplastic anemia: a retrospective study1
Adding rhTPO to CsA’+ hetrombopag improves platelet recovery and early hematologic responses, supporting its potential role in optimizing the initial management of patients with TD-NSAA.
- Efficacy and safety of bruton tyrosine kinase (BTK) inhibitor zanubrutinib in relapsed/refractory warm autoimmune hemolytic anemia (wAIHA) after multiple lines of therapy: A prospective phase 2 single-arm study1
Zanubrutinib demonstrated modest activity at 12 weeks in heavily pre-treated R/R wAIHA patients, with manageable toxicity.
- Computational exploration and molecular dynamics simulations for investigating the potential inhibitory mechanism of amantadine on the ion channel activity of bovine viral diarrhea virus p71
A potential ion channel model is proposed in which E21, Y25 and R34 are hypothesized to selectively recruit and dehydrate ions, while residue L28 acts as a hydrophobic restrictor, limiting the free movement of water.
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- Bacterial lipoate protein ligases rescue lipoylation and respiration deficiency in mammals1
Systematic characterization of lipoylation deficiency is provided and the way to gene therapy for treatment of lipoylation-deficient patients is paves the way to gene therapy for treatment of lipoylation-deficient patients.
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- Advances in artificial intelligence for neuroimaging–
This review surveys recent advances and emerging trends across diverse neuroimaging modalities, including multimodal studies that integrate imaging with clinical and molecular data and highlights priorities for developing reliable, generalizable, and interpretable that can advance both neuroimaging research and real-world patient care.
- Full-length structure of CPR-containing self-sufficient cytochrome P450–
The structure of a homologue of the most extensively studied P450BM3 from Shimazuella soli is resolved by single particle cryo-electron microscopy and X-ray crystallography and a class of structure that lacks one heme-domain was identified from the cryo-EM analyses, indicating that the heme-domain is mobile.
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- Selinexor in combination with azacitidine or Ruxolitinib for Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes: A Multi-Center Prospective Exploratory Study–
The combination of selinexor with azacitidine or ruxolit in combination with either azacitidine or ruxolitinib showed good efficacy and safety in MDS/MPN patients.
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- Treatment with sirolimus for refractory/relapsed primary or secondary warm autoimmune hemolytic anemia/evans syndrome: A single centre prospective study–
Sirolimus was effective for patients with primary refractory/relapsed wAIHA and ES, with mild side effects and low relapse rate, and no factors were found to predict significantly OR, CR at 6-month.
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- High expression levels of centromere protein O participates in cell activity of human ovarian cancer–
- SimMAT: Exploring Transferability from Vision Foundation Models to Any Image Modality–
SimMAT can improve the segmentation performance (mIoU) from 22.15% to 53.88% on average for evaluated modalities and consistently outperforms other baselines and can raise awareness of cross-modal transfer learning and benefit various fields for better results with vision foundation models.
- High-Fidelity Virtual Try-on with Large-Scale Unpaired Learning–
Boosted Virtual Try-on shows great generalizability and scalability to various dressing styles and data sources, and an unpaired try-on synthesizer by constructing pseudo training pairs with randomly misaligned on-model clothes, where intricate skin texture and clothes boundaries can be generated.
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- Long-Term Real-World Follow-up Study of Luspatercept for Lower-Risk Myelodysplastic Neoplasms–
Over time, patients treated with luspatercept had a significant increase in hemoglobin level compared with that of the baseline at the 1st 2nd, 3rd, 6th, and 12th month, and at the end of follow-up, and luspatercept was effective for refractory MDS patients.
Publication data from OpenAlex, with missing venues and authors filled in from Crossref; citation counts are the higher of OpenAlex and Semantic Scholar, last synced 2026-10-12. One-sentence summaries under some papers are written by Semantic Scholar’s model. Citation counts may be lower than on Google Scholar, which indexes more sources.
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